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Lee, Semin 이세민

  • Assistant Professor
  • Cancer genomics & single-cell genomics
  • Current Research Interests
  • Cancer genomics & single-cell genomics


  • Biographical Sketch
    • 2016-present: Assistant Professor, Biomedical Engineering, UNIST, Korea
    • 2011-2016: Research Fellow, Department of Biomedical Informatics, Harvard Medical School, USA (Advisor: Professor Peter J. Park)
    • 2011: PhD in Biochemistry, Department of Biochemistry, University of Cambridge (Advisor: Professor Sir Tom L. Blundell, FRS, FMedSci)
    • 2005: MSc in Bioinformatics, Department of BioSystems, KAIST, (Advisor: Professor Jong Bhak)
    • 2003: BA in Biological Sciences, Seoul National University, Korea


  • Selected Publications

Lodato MA*, Woodworth MB*, Lee S*, Evrony GD, Mehta BK, Karger A, Lee S, Chittenden TW, Cai X, Luquette LJ, Lee E, Park PJ, Walsh CA. Mosaic Mutations Trace Developmental and Transcriptional Histories of Single Human Neurons. Science. 2015 Oct 2;350(6256):94-8. (*Co-first authors)

The Cancer Genome Atlas Network. Comprehensive molecular profiling of lung adenocarcinoma. Nature. Jul 31;511(7511):543-50.

The Cancer Genome Atlas Network. Comprehensive molecular characterization of urothelial bladder carcinoma. Nature. 2014 Mar 20;507(7492):315-22.

Lee S and Bolanos-Garcia VM. The dynamics of signal amplification by macromolecular assemblies for the control of chromosome segregation. Front Physiol. 2014 Sep 29;5:368.

Lee S, Thebault P, Freschi L, Beaufils S, Blundell TL, Landry CR, Bolanos-Garcia VM, Elowe S. Characterization of the Spindle Checkpoint Kinase Mps1 Reveals a Domain with Functional and Structural Similarities to the Tetratricopeptide Repeat Motifs of the Bub1 and BubR1 Checkpoint Kinases. Journal of Biological Chemistry 2012 Feb 17;287(8):5988-6001.

Park D*, Lee S*, Bolser D, Schroeder M, Lappe M, Oh D, Bhak J. (2005) Comparative interactomics analysis of protein family interaction networks using PSIMAP (protein structural interactome map). Bioinformatics 2005 Aug 1;21(15):3234-40. (*Co-first authors)