View source for George Church

<p>(1954- ) is an American molecular geneticist. He is currently Professor of Genetics <sup class="reference" id="_ref-0">[1]</sup> at Harvard Medical School and Professor of Health Sciences &amp; Technology <sup class="reference" id="_ref-HST_0">[2]</sup> at Harvard and MIT. With Walter Gilbert he developed the first direct genomic sequencing method in 1984<sup class="reference" id="_ref-1">[3]</sup> and helped initiate the Human Genome Project in 1984 <sup class="reference" id="_ref-2">[4]</sup> while he was a Research Scientist at newly-formed Biogen Inc. He invented the broadly-applied concepts of molecular multiplexing and tags<sup class="reference" id="_ref-3">[5]</sup>, homologous recombination methods <sup class="reference" id="_ref-4">[6]</sup>, and DNA array synthesizers. Technology transfer of automated sequencing &amp; software to Genome Therapeutics Corp. resulted in the first commercial genome sequence, (the human pathogen, <em>Helicobacter pylori</em>) in 1994 <sup class="reference" id="_ref-NG_0">[7]</sup>. He initiated the Personal Genome Project (PGP) <sup class="reference" id="_ref-5">[8]</sup> in 2005 and research on synthetic biology. He is director of the U.S. Department of Energy Center on Bioenergy at Harvard &amp; MIT <sup class="reference" id="_ref-6">[9]</sup> and director of the National Institutes of Health (NHGRI) Center of Excellence in Genomic Science at Harvard, MIT &amp; Washington University <sup class="reference" id="_ref-7">[10]</sup>. He has been advisor to 22 companies, most recently co-founding (with Joseph Jacobson, Jay Keasling, and Drew Endy) Codon Devices, a biotech startup dedicated to synthetic biology<sup class="reference" id="_ref-8">[11]</sup> and (with Chris Somerville) founding LS9, which is focused on biofuels <sup class="reference" id="_ref-9">[12]</sup>. He is a senior editor for Nature EMBO Molecular Systems Biology. </p>
<h2><span class="mw-headline">External links</span></h2>
<ul>
    <li>[http://en.wikipedia.org/wiki/George_Church George Church in Wikipedia.org]</li>
    <li><a class="external text" title="http://arep.med.harvard.edu/" rel="nofollow" href="http://arep.med.harvard.edu/">Church Lab webpage</a> </li>
    <li><a class="external text" title="http://arep.med.harvard.edu/Polonator/" rel="nofollow" href="http://arep.med.harvard.edu/Polonator/">New Polony DNA Sequencing Methods</a> </li>
    <li><a class="external text" title="http://edge.org/3rd_culture/bios/church.html" rel="nofollow" href="http://edge.org/3rd_culture/bios/church.html">Biosketch on Edge.org</a> </li>
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<p><a id="References" name="References"></a></p>
<h2><span class="mw-headline">References</span></h2>
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<ol class="references">
    <li id="_note-0"><strong><a title="" href="http://en.wikipedia.org/wiki/George_Church#_ref-0">^</a></strong> <a class="external text" title="http://genetics.med.harvard.edu/faculty.htm#C" rel="nofollow" href="http://genetics.med.harvard.edu/faculty.htm#C">HMS Genetics Faculty</a> </li>
    <li id="_note-HST"><strong><a title="" href="http://en.wikipedia.org/wiki/George_Church#_ref-HST_0">^</a></strong> <a class="external text" title="http://hst.mit.edu/servlet/ControllerServlet?handler=PeopleHandler&amp;action=viewOne&amp;id=HST000211" rel="nofollow" href="http://hst.mit.edu/servlet/ControllerServlet?handler=PeopleHandler&amp;action=viewOne&amp;id=HST000211">HST</a> </li>
    <li id="_note-1"><strong><a title="" href="http://en.wikipedia.org/wiki/George_Church#_ref-1">^</a></strong> <cite style="FONT-STYLE: normal">Church GM, Gilbert W (1984). &quot;Genomic Sequencing&quot;. <em>Proc Nat Acad Sci USA</em> <strong>81</strong>: 1991-5. <a class="external" title="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=6326095" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=6326095">PMID 6326095</a>.</cite> </li>
    <li id="_note-2"><strong><a title="" href="http://en.wikipedia.org/wiki/George_Church#_ref-2">^</a></strong> <cite style="FONT-STYLE: normal">Cook-Deegan RM (1989). &quot;The Alta summit, December 1984&quot;. <em>Genomics</em> <strong>5</strong>: 661-3. <a class="external" title="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=2613249" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=2613249">PMID 2613249</a>.</cite> </li>
    <li id="_note-3"><strong><a title="" href="http://en.wikipedia.org/wiki/George_Church#_ref-3">^</a></strong> <cite style="FONT-STYLE: normal">Church GM, Kieffer-Higgins S. (1984). &quot;Multiplex Sequencing&quot;. <em>Science</em> <strong>240</strong>: 185-8. <a class="external" title="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=3353714" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=3353714">PMID 3353714</a>.</cite> </li>
    <li id="_note-4"><strong><a title="" href="http://en.wikipedia.org/wiki/George_Church#_ref-4">^</a></strong> <cite style="FONT-STYLE: normal">Link AJ, Phillips D, Church GM (1997). &quot;Methods for generating precise deletions and insertions in the genome of wild-type <em>Escherichia coli</em>: application to open reading frame characterization&quot;. <em>J Bacteriol.</em> <strong>179</strong>: 6228-37. <a class="external" title="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=9335267" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=9335267">PMID 9335267</a>.</cite> </li>
    <li id="_note-NG"><strong><a title="" href="http://en.wikipedia.org/wiki/George_Church#_ref-NG_0">^</a></strong> <cite style="FONT-STYLE: normal">(1996) &quot;Capitalizing on the genome&quot;. <em>Nature Genetics</em> <strong>13</strong>: 1. <a class="external" title="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=8673083" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=8673083">PMID 8673083</a>.</cite><a class="external autonumber" title="http://www.nature.com/ng/wilma/v13n1.867861436.html" rel="nofollow" href="http://www.nature.com/ng/wilma/v13n1.867861436.html">[1]</a> </li>
    <li id="_note-5"><strong><a title="" href="http://en.wikipedia.org/wiki/George_Church#_ref-5">^</a></strong> <cite style="FONT-STYLE: normal">Church GM (2005). &quot;The personal genome project&quot;. <em>Mol Syst Biol.</em> <strong>1</strong>: 0030. <a class="external" title="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=16729065" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=16729065">PMID 16729065</a>.</cite> </li>
    <li id="_note-6"><strong><a title="" href="http://en.wikipedia.org/wiki/George_Church#_ref-6">^</a></strong> <a class="external text" title="http://arep.med.harvard.edu/DOEGTL/" rel="nofollow" href="http://arep.med.harvard.edu/DOEGTL/">DOE Genomes to Life Center</a> </li>
    <li id="_note-7"><strong><a title="" href="http://en.wikipedia.org/wiki/George_Church#_ref-7">^</a></strong> <a class="external text" title="http://www.genome.gov/12511135" rel="nofollow" href="http://www.genome.gov/12511135">Centers of Excellence in Genomic Science Awards</a> </li>
    <li id="_note-8"><strong><a title="" href="http://en.wikipedia.org/wiki/George_Church#_ref-8">^</a></strong> <cite style="FONT-STYLE: normal">Herper M (2006). &quot;Photoshop For DNA&quot;. <em>Forbes</em>.</cite><a class="external autonumber" title="http://www.forbes.com/sciencesandmedicine/2005/06/01/cx_mh_0601dna.html" rel="nofollow" href="http://www.forbes.com/sciencesandmedicine/2005/06/01/cx_mh_0601dna.html">[2]</a> </li>
    <li id="_note-9"><strong><a title="" href="http://en.wikipedia.org/wiki/George_Church#_ref-9">^</a></strong> <a class="external text" title="http://sanfrancisco.bizjournals.com/sanfrancisco/stories/2007/03/12/daily3.html?b=1173672000%5e1430618&amp;surround=etf" rel="nofollow" href="http://sanfrancisco.bizjournals.com/sanfrancisco/stories/2007/03/12/daily3.html?b=1173672000%5e1430618&amp;surround=etf">San Francisco Business Times - March 12, 2007</a> </li>
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