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,Created page with " '''HyoJung Ryu''' ---- <u>'''Education'''</u> *2011/03 - 2018/08 : Combined '''M.S/Ph.D.''' in Bioinformatics, UST (University of Science and..."
'''HyoJung Ryu'''
----
<u>'''Education'''</u>
*2011/03 - 2018/08 : Combined '''M.S/Ph.D.''' in Bioinformatics, UST (University of Science and Technology) KRIBB school, Daejeon, Korea
*2009/05 - 2011/02 : '''B.S. '''in Computer Science, NILE (National Institute for Lifelong Education), Seoul, Korea
<u>'''Career'''</u>
*2019/04 - Present : Post-doctoral researcher, UNIST KOGIC, Ulsan, Korea
*2018/10 - 2019/02 : Researcher, KRIBB, Daejeon, Korea
----
<u>'''Research topics'''</u>
#Development of prediction score of protein function change by a genetic mutation
*Protein 3D structure modeling
**I-TASSER, RaptorX, Rosetta
*Evaluation of protein structural features ( Geometrical/Stereo-chemical features)
**PROCHECK, WHAT_CHECK, MolProbity
*Scoring function development
<img style="null" src=http://in.kogic.kr/ckfinder/userfiles/images/Concept_figure_2(1).png>
2. Antigenic peptide-MHC binding affinity prediction with MD
*Molecular Dynamics(MD) simulation
**Gromacs(2019.03 ver), Tinker
*Binding affinity prediction
**FoldX
*IEDB big data
**HLA-A type peptide list
***Specific alleles : HLA-A*02:01, HLA-A*02:24
''' '''
'''<img style="null" src=http://in.kogic.kr/ckfinder/userfiles/images/Concept.png>'''
2-1. Workflow - Generate reference set (MHC class I)
<img style="null" src=http://in.kogic.kr/ckfinder/userfiles/images/Refset_generation.png>
