박종화

From kogic.kr

박종화(Jong Bhak)

1. 인적사항

성    명

    박종화
생년월일
1967년 5월 20일
소속기관
 울산과학기술원/ 게놈연구재단
직    위
 교수 / 센터장
전화번호
 010 4644 6754
FAX
 052-217-3229
이동전화
 010 4644 6754
E-mail

2. 학력/경력

연도
학교/기관
전공/직위
학위/비고
1986-1987
서울대학교 수의과대학
수의학과
군대 및 유학을 위해 자퇴
1990-1994
영국 애버딘(Aberdeen) 대학교
생화학과
학사
1994-1997
영국 케임브리지 대학교 MRC 센터
생정보학 (bioinformatics)
박사
1998-1999
미국 하바드의대 유전학과(조지 처치랩)
생정보학/게놈학
박사후 연구원
1999-2001
유럽생정보학 연구소(EBI)
생정보학
박사후 연구원
2001-2003
영국 케임브리지 MRC 센터
생정보학/게놈학
연구실장 (종신)
2003-2005

KAIST

생정보학
교수
2005-2009
한국생명공학연구원 KOBIC
생정보학
센터장
2009-2014
(주)테라젠이텍스,
게놈사업부
사장/연구소장
2009-현재
(재) 게놈연구재단
생정보학
연구소장
2012-2014

서울대 융합대학원 나노 사이언스과
생정보학
겸임교수
2014-현재
울산과기원(UNIST), 교수
생정보학/ 게놈학
정교수

3. 주요 연구/ 산업화 실적 또는 대표 논문

1. 한국인 미만성 위암게놈 분석 (2014년 Genome Biology)

2. 게놈해독/분석 서비스 개발(상용화 서비스 제공중)

3. 최초 한국인 게놈 분석 (2009년 Genome Research)
4. 최초 호랑이 표준게놈지도 작성 (2013년 Nature Communications)
5. 최초 고래 표준게놈지도 작성(2014년 Nature Genetics)

6. 대중화된 게놈, 건강정보서비스 개발(헬로진:테라젠, 상용화 서비스 제공중)

7 산전진단 상품개발(유전자정보활용, 상용화 서비스 제공중)
 
주요관심분야: 노화체학(Geromics), 게놈학(Genomics), 생정보학(Bioinformatics)
 

목표: 생정보학을 이용한 게놈/노화 상용/산업화 관련 상품개발 및 국가적 (큰규모) 인프라 구축.

 게놈 분석 및 의학 응용한 상업화 (기업: 제로믹스)

4. List of publication

(Note: before 2005, I spelled my surname Park and occasionally used Jonghwa as my first name.)

114) Genome-wide analysis of DNA methylation patterns in horse.

Ja-Rang Lee, Chang Pyo Hong, Jae-Woo Moon, Yi-Deun Jung, Dae-Soo Kim, Tae-Hyung Kim, Jeong-An Gim, Jin-Han Bae, Yuri Choi, JungwooEo, Yun-Jeong Kwon, Sanghoon Song, JunsuKo, Young Mok Yang, Hak-Kyo Lee, Kyung-Do Park, Kung Ahn, Kyoung-Tag Do, Hong-Seok Ha, Kyudong Han, JooMi Yi, Hee-Jae Cha, Byung-Wook Cho, Jong Bhak* and Heui-Soo Kim*.

BMC Genomics 2014, 15:598  doi:10.1186/1471-2164-15-598, 15 July 2014

 

113)Identification and Characterization of MicroRNAs in Normal Equine Tissues by Next Generation Sequencing

Myung-Chul Kim, Seung-Woo Lee, Doug-YoungRyu, Feng-Ji Cui, JongBhak and Yongbaek Kim - PLOS ONE, 2014Published: April 02, 2014 DOI: 10.1371/journal.pone.0093662

 

112) Genomic profile analysis of diffuse-type gastric cancers

Yeon-Su Lee†, Yun Sung Cho†, Geon Kook Lee†, Sunghoon Lee†, Young-Woo Kim, SungwoongJho, Hak-Min Kim, Seung-Hyun Hong, Jung-Ah Hwang, Sook-young Kim, Dongwan Hong, Il Ju Choi, ByungChul Kim, Byoung-Chul Kim, Chul Hong Kim, Hansol Choi, Youngju Kim, Kyung Wook Kim, Gu Kong, HyungLae Kim, Jong Bhak*, SeungHoon Lee* and Jin Soo Lee. Genome Biology, 2014

 

111) Minke whale genome and aquatic adaptation in cetaceans.

Hyung-Soon Yim1,24, Yun Sung Cho2,24, Xuanmin Guang3,24, Sung Gyun Kang1,4, Jae-Yeon Jeong1,4, Sun-Shin Cha1,4,5, Hyun-Myung Oh1, Jae-Hak Lee1, Eun Chan Yang1, KaeKyoung Kwon1,4, Yun Jae Kim1, Tae Wan Kim1, Wonduck Kim1, Jeong Ho Jeon1, Sang-Jin Kim1,4, Dong Han Choi1, Sungwoong Jho2, Hak-Min Kim2, Junsu Ko6, Hyunmin Kim6, Young-Ah Shin2, Hyun-Ju Jung6, Yuan Zheng3, Zhuo Wang3, Yan Chen3, Ming Chen3, Awei Jiang3, Erli Li3, Shu Zhang3, Haolong Hou7, Tae Hyung Kim6, Lili Yu3, Sha Liu3,Kung Ahn6, Jesse Cooper6, Sin-Gi Park6, Chang Pyo Hong6, Wook Jin8, Heui-Soo Kim9, Chankyu Park10, Kyooyeol Lee10, Sung Chun11, Phillip Morin12, Stephen J. O’Brien13, Hang Lee14, Jumpei Kimura15, DaeYeon Moon16, Andrea Manica17, Jeremy Edwards18, ByungChul Kim2, Sangsoo Kim19, Jun Wang3,20,21, Jong Bhak2,6,22,23,*, Hyun Sook Lee1,4,*& Jung-Hyun Lee1,4,*Nature Genetics, 2013. (24th Nov 2013)

110) Whole genome comparison of donor and cloned dogs

Hak-Min Kim, Yun Sung Cho,                Hyunmin Kim, SungwoongJho,Bongjun Son, Joung Yoon Choi,Sangsoo Kim, Byeong Chun Lee,Jong Bhak& Goo Jang

Scientific Reports 3, Article number: 2998doi:10.1038/srep02998.  October 2013

 

109) Tiger genome and comparative analysis with lion and snow leopard genomes.

Yun Sung Cho1, Li Hu2, Haolong Hou2, Hang Lee3, Jiaohui Xu2, Soowhan Kwon4, Sukhun Oh4, Hak-Min Kim1, Sungwoong Jho1, Sangsoo Kim5, Young-Ah Shin1, ByungChul Kim1,6, Hyunmin Kim6, Chang-uk Kim1, Shu-Jin Luo7, Warren E. Johnson8, Klaus-Peter Koepfli9, Anne Schmidt-Küntzel10, Jason A. Turner11, Laurie Marker12, Cindy Harper13, Susan M. Miller13,14, Wilhelm Jacobs15, Laura D. Bertola16, Tae Hyung Kim6, Sunghoon Lee1,6, Qian Zhou2, Hyun-Ju Jung6, Xiao Xu7, Priyvrat Gadhvi1, Pengwei Xu2, Yingqi Xiong2, Yadan Luo2, Shengkai Pan2, Caiyun Gou2, Xiuhui Chu2, Jilin Zhang2, Sanyang Liu2, Jing He2, Ying Chen2, Linfeng Yang2, Yulan Yang2, Jiaju He2, Sha Liu2, Junyi Wang2, Chul Hong Kim6, Hwanjong Kwak6, Jong-Soo Kim1, Seungwoo Hwang17, Junsu Ko6, Chang-Bae Kim18, Sangtae Kim19, Damdin Bayarlkhagva20,WoonKee Paek21,Seong-Jin Kim6,22, Stephen J. O’Brien9,Jun Wang2,23,24&Jong Bhak1,6,25*Nature Communications, 2013. Sep. 17th.

 
108) iAnn: an event sharing platform for the life sciences.

Jimenez RC, Albar JP, Bhak J,Blatter MC, Blicher T, Brazas MD, Brooksbank C, Budd A, De Las Rivas J, Dreyer J, van Driel MA, Dunn MJ, Fernandes PL, van Gelder CW, Hermjakob H, Ioannidis V, Judge DP, Kahlem P, Korpelainen E, Kraus HJ, Loveland J, Mayer C, McDowall J, Moran F, Mulder N, Nyronen T, Rother K, Salazar GA, Schneider R, Via A, Villaveces JM, Yu P, Schneider MV, Attwood TK, Corpas M.

Bioinformatics. 2013 Aug 1;29(15):1919-1921. Epub2013 Jun 5.

 

107) Comprehensive genome- and transcriptome-wide analyses of mutations associated with microsatellite instability in Korean gastric cancers.

Yoon K, Lee S, Han TS, Moon SY, Yun SM, Kong SH, Jho S, Choe J, Yu J, Lee HJ, Park JH, Kim HM, Lee SY, Park J, Kim WH, Bhak J, Yang HK, Kim SJ.

Genome Res. 2013 Jun 4.
 

106) The genetic basis of white tigers.

Xu X, Dong GX, Hu XS, Miao L, Zhang XL, Zhang DL, Yang HD, Zhang TY, Zou ZT, Zhang TT, Zhuang Y, Bhak J, Cho YS, Dai WT, Jiang TJ, Xie C, Li R, Luo SJ.

Curr Biol. 2013 Jun 3;23(11):1031-5. doi: 10.1016/j.cub.2013.04.054. Epub 2013 May 23.

 

105)Peeling back the evolutionary layers of molecular mechanisms responsive to exercise-stress in the skeletal muscle of the racing horse.

Kim H, Lee T, Park W, Lee JW, Kim J, Lee BY, Ahn H, Moon S, Cho S, Do KT, Kim HS, Lee HK, Lee CK, Kong HS, Yang YM, Park J, Kim HM, Kim BC, Hwang S, Bhak J, Burt D, Park KD, Cho BW, Kim H.

DNA Res. 2013;20(3):287-98. doi: 10.1093/dnares/dst010. Epub 2013 Apr 11.
 

104) Whole transcriptome analyses of six thoroughbred horses before and after exercise using RNA-Seq(corresponding)

Park KD, Park J, Ko J, Kim BC, Kim HS, Ahn K, Do KT, Choi H, Kim HM, Song S, Lee S, Jho S, Kong HS, Yang YM, Jhun BH, Kim C,Kim TH, Hwang S, Bhak* J, Lee* HK, and Cho* BW.
BMC Genomics.  2012 Sep 12;13:473. doi: 10.1186/1471-2164-13-473.
 
103) A public resource facilitating clinical use of genomes.
 
102) Genetic dating indicates that the Asian-Papuan admixture through Eastern Indonesia corresponds to the Austronesian expansion.
 
101) MetaBase--the wiki-database of biological databases.
 
100) Liverome: a curated database of liver cancer-related gene signatures with self-contained context information.
 
 
98) De novo transcriptome sequencing of Momordicacochinchinensis to identify genes involved in the carotenoid biosynthesis. Hyun TK, Rim Y, Jang HJ, Kim CH, Park J, Kumar R, Lee S, Kim BC, Bhak J, Nguyen-Quoc B, Kim SW, Lee SY, Kim JY.
 

97) Mutational hotspots in the mitochondrial genome of lung cancer. Choi SJ, Kim SH, Kang HY, Lee J, Bhak JH, Sohn I, Jung SH, Choi YS, Kim HK, Han J, Huh N, Lee G, Kim BC, Kim

J. BiochemBiophys Res Commun.2011 Apr 1;407(1):23-7. Epub 2011 Feb 18.
 

96) Population genetic structure of peninsular Malaysia Malay sub-ethnic groups. Hatin WI, Nur-Shafawati AR, Zahri MK, Xu S, Jin L, Tan SG, Rizman-Idid M, Zilfalil BA; HUGO Pan-Asian SNP Consortium. PLoS One.2011 Apr 5;6(4):e18312.

 

95) BetaDock: shape-priority docking method based on beta-complex. Kim DS, Kim CM, Won CI, Kim JK, Ryu J, Cho Y, Lee C, Bhak J.

J BiomolStructDyn. 2011 Aug;29(1):219-42.
 

94) PanSNPdb: the Pan-Asian SNP genotyping database. Ngamphiw C, Assawamakin A, Xu S, Shaw PJ, Yang JO, Ghang H, Bhak J, Liu E, Tongsima S; HUGO Pan-Asian SNP Consortium. 

PLoS One. 2011;6(6):e21451. Epub 2011 Jun 23.
 

93) Gene expression pattern in transmitochondrial cytoplasmic hybrid cells harboring type 2 diabetes-associated mitochondrial DNA haplogroups.

Hwang S, Kwak SH, Bhak J, Kang HS, Lee YR, Koo BK, Park KS, Lee HK, Cho YM. 

PLoS One. 2011;6(7):e22116. Epub2011 Jul 13.
 

92) Protein network prediction and topological analysis in Leishmania major as a tool for drug target selection. Flórez AF, Park D, Bhak J, Kim BC, Kuchinsky A, Morris JH, Espinosa J, Muskus C. 

BMC Bioinformatics. 2010 Sep 27;11:484.
 

91) Whole-genome sequencing and intensive analysis of the undomesticated soybean (Glycine sojaSieb. and Zucc.) genome. Moon Young Kima,1, Sunghoon Leeb,1,2, Kyujung Vana,1, Tae-HyungKimb,1,2, Soon-Chun Jeongc, Ik-Young Choid, Dae-SooKimb, Yong-SeokLeeb, DaeuiParkb, Jianxin Mae, Woo-YeonKimb, Byoung-ChulKimb, SungjinParkb, Kyung-A Leeb, Dong Hyun Kima, Kil Hyun Kima, Jin HeeShina, Young EunJanga, Kyung Do Kima, Wei Xian Liua, TanaponChaisana, Yang Jae Kanga, Yeong-Ho Leea, Kook-HyungKimf, Jung-Kyung Moong, Jeremy Schmutzh, Scott A. Jacksone, Jong Bhak* and Suk-Ha Lee*.

ProcNatlAcadSci U S A. 2010 Dec 21;107(51):22032-7. Epub2010 Dec 3.
 

90) A proposal for the revision of molecular boundary typology.

Kim DS, Won CI, and Bhak J.

J BiomolStructDyn.2010 Oct;28(2):277-88.


89) Gene Flow between the Korean Peninsula and Its Neighboring Countries. Jongsun Jung, Hoyoung Kang, Yoon Shin Cho, JiHee Oh, Min HyungRyu, Hye Won Chung, Jeong-Sun Seo, Jong-Eun Lee, Bermseok Oh, Jong Bhak, and Hyung-Lae Kim*.

PLoS ONE 5(7):e11855.doi:10.1371/journal.pone.0011855. 20100729

88) PDBWiki: added value through community annotation of the Protein Data Bank.

Henning Stehr,*, Jose M. Duarte1, Michael Lappe1, Jong Bhak,* and Dan M. Bolser.

Database, Vol. 2010:baq009; doi:10.1093/database/baq009.

 

87) Differential evolutionary rates of neuronal transcriptome in Aplysiakurodai and Aplysiacalifornica as a tool for gene mining.

Choi SL, Lee YS, Rim YS, Kim TH, Moroz LL, Kandel ER, Bhak J, and Kaang BK.

J Neurogenet. 2010 Jul;24(2):75-82. doi: 10.3109/01677061003770614.

 

86) Sphericity of a protein via the beta-complex.

Kim DS, Kim JK, Won CI, Kim CM, Park JY, Bhak J.

J Mol Graph Model. 2010 Apr;28(7):636-49. doi: 10.1016/j.jmgm.2010.01.001. Epub 2010 Jan 15.


85) Mapping Human Genetic Diversity in Asia. The HUGO Pan-Asian SNP Consortium. Science. 2009. Dec. 11th. (As the Korean Principal Investigator)http://www.ncbi.nlm.nih.gov/pubmed/20007900

84) PDbase: a database of Parkinson's Disease-related genes and genetic variation using substantianigra ESTs.Yang JO, Kim WY, Jeong SY, Oh JH, Jho S, Bhak J*, and Kim NS*.BMC Genomics 2009, 10(Suppl 3):S32 (3 December 2009).

83) MitoInteractome: Mitochondrial protein interactome database, and its application in 'aging network' analysis. Reja R, Venkatakrishnan AJ, Lee J, Kim BC, Ryu JW, Gong S,Bhak J*, and  Park D*.BMC Genomics 2009, 10(Suppl 3):S20 (3 December 2009).

82) PutidaNET: Interactome database service and network analysis of Pseudomonas putida KT2440.Park SJ, Choi JS, Kim BC, Jho SW, Ryu JW, Park D, Lee KA, Bhak J*, and Kim SI*.BMC Genomics 2009, 10(Suppl 3):S18 (3 December 2009).

81) The Korean Bird Information System (KBIS) through open and public participation. Paik IH, Lim J, Chun BS, Jin SD, Yu JP, Lee JW, Bhak J, and Paek WK.BMC Bioinformatics 2009, 10(Suppl 15):S11 (3 December 2009).

80) Gevab: a prototype genome variation analysis browsing server. Kim WY, Kim SY, Kim TH, Ahn SM, Byun HN, Kim D, Kim DS, Lee YS, Ghang H, Park D, Kim BC, Kim C, Lee S, Kim SJ, and Bhak J*.BMC Bioinformatics 2009, 10(Suppl 15):S3 (3 December 2009). 

79) MitoVariome: a variome database of human mitochondrial DNA. Lee YS, Kim WY, Ji M, Kim JH, and Bhak J*.BMC Genomics 2009, 10(Suppl 3):S12 (3 December 2009).

78) COMUS: Clinician-Oriented locus-specific MUtation detection and deposition System.
Jho S, Kim BC, Ghang H, Kim JH, Park D, Kim HM, Jung S, Yoo K, Kim HJ, Lee S, and Bhak J*. BMC Genomics 2009, 10(Suppl 3):S35 (3 December 2009).

77)BioBarcode: a general DNA barcoding database and server platform for Asian biodiversity resources.Lim J, Kim SY, Kim S, Eo HS, Kim CB, Paek WK, Kim W*, and Bhak J*.BMC Genomics 2009, 10(Suppl 3):S8 (3 December 2009).

76)ssSNPTarget: Genome-Wide Splice-Site Single Nucleotide Polymorphism Database.Ok Yang J, Kim WY, and Bhak J. Human mutation, 2009 Sep. 16th, PMID: 19760752.

75) The first Korean genome sequence and analysis: Full genome sequencing for a socio-ethnic group. Sung-Min Ahn, Tae-Hyung Kim, Sunghoon Lee, Deokhoon Kim, Ho Ghang, Daesoo Kim, Byoung-Chul Kim, Sang-Yoon Kim, Woo-Yeon Kim, Chulhong Kim, Daeui Park, Yong Seok Lee, Sangsoo Kim, RohitReja, SungwoongJho, Chang Geun Kim, Ji-Young Cha, Kyung-Hee Kim, Bonghee Lee, Jong Bhak*, and Seong-Jin Kim*. Genome Research, May 26, 2009. PMID: 19470904.

74) Planning the Human Variome Project: The Spain report. Kaput J, Cotton RG, Hardman L, Watson M, Al Aqeel AI, Al-Aama JY, Al-Mulla F, Alonso S, Aretz S, Auerbach AD, Bapat B, Bernstein IT, Bhak J, Bleoo SL, Blöcker H, Brenner SE, Burn J, Bustamante M, Calzone R, Cambon-Thomsen A, Cargill M, Carrera P, Cavedon L, Cho YS, Chung YJ, Claustres M, Cutting G, Dalgleish R, den Dunnen JT, Díaz C, Dobrowolski S, Dos Santos MR, Ekong R, Flanagan SB, Flicek P, Furukawa Y, Genuardi M, Ghang H, Golubenko MV, Greenblatt MS, Hamosh A, Hancock JM,Hardison R, Harrison TM, Hoffmann R, Horaitis R, Howard HJ, Barash CI, Izagirre N, Jung J, Kojima T, Laradi S, Lee YS, Lee JY, Gil-da-Silva-Lopes VL, Macrae FA, Maglott D, Marafie MJ, Marsh SG, Matsubara Y, Messiaen LM, Möslein G, Netea MG, Norton ML, Oefner PJ, Oetting WS, O'Leary JC, de Ramirez AM, Paalman MH, Parboosingh J, Patrinos GP, Perozzi G, Phillips IR, Povey S, Prasad S, Qi M, Quin DJ, Ramesar RS, Richards CS, Savige J, Scheible DG, Scott RJ, Seminara D, Shephard EA, Sijmons RH, Smith TD, Sobrido MJ, Tanaka T, Tavtigian SV, Taylor GR, Teague J, Töpel T, Ullman-Cullere M, Utsunomiya J, van Kranen HJ, Vihinen M, Webb E, Weber TK, Yeager M, Yeom YI, Yim SH, Yoo HS; on behalf of contributors to the Human Variome Project Planning Meeting. Hum Mutat. 2009 March 20; 30(4):496-510.  PMID: 19306394 [PubMed - indexed for MEDLINE].

73) Kinetics of Zn2+ -induced Brain Type Creatine Kinase Unfolding and Aggregation. Mu H, Lü ZR, Park D, Kim BC, Bhak J, Zou F, Yang JM, Li S, Park YD, Zou HC, Zhou HM. ApplBiochemBiotechnol. 2009 Mar 11.

72) Profiling the dysregulated genes of keratinocytes in atopic dermatitis patients: cDNA microarray and interactomic analyses. Lü ZR, Park D, Lee KA, Ryu JW, Bhak J, Shi L, Lee DY, Park YD, Zou F, Yang JM. J Dermatol Sci. 2009Jan 19.

71) The effects of acrylamide on brain creatine kinase: Inhibition kinetics and computational docking simulation. Zhi-RongLüa, He-Chang Zou, Seong Jin Park, Daeui Park, Long Shi, Sang Ho Oh, Yong-Doo Park, Jong Bhak, and FeiZou, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2009, 44(2):128-132.

70) Dysregulated genes of extrinsic type of atopic dermatitis: 34K microarray and interactomic analyses. Zhi-Rong Lü1, a, Tae-Ho Park1, b, Eil-SooLeec, Kea-JeungKimb, DaeuiParkd, Byoung-ChulKim, Seong-WoongChod, Jong Bhak, Yong-Doo Park, FeiZoua, and Jun-Mo Yang. Journal of Dermatological Science, 2009, 53(2):146-165.

69) Personal Genomics, Bioinformatics, and Variomics. Jong Bhak, Ho Ghang, RohitReja, and Sangsoo Kim.Genomics & Informatics, 2008, 6(4):161-165.

68) An integrated korean biodiversity and genetic information retrieval system. Jeongheui Lim, Jong Bhak, Hee-Mock Oh, Chang-Bae Kim, Yong-Ha Park, and WoonKeePaek. BMC Bioinformatics, 2008, 9(12):S24.

67) An integrated database-pipeline system for studying single nucleotide polymorphisms and diseases. Jin Ok Yang, Sohyun Hwang, Jeongsu Oh, Jong Bhak, and Tae-Kwon Sohn.BMC Bioinformatics, 2008, 9(12):S19.

66) Prediction and evaluation of protein-protein interaction in keratinocyte differentiation. Hyun Kyung Yoon, Kyung-CheolSohn, Jung-Suk Lee, Yu Jin Kim, Jong Bhak, Jun-Mo Yang, Kwan-Hee You, Chang-Deok Kim, Jeung-Hoon Lee.BBRC, 2008,377(2):662-667.

65) Transcriptome analysis and identification of regulators for long-term plasticity in Aplysiakurodai. Yong-seok Lee, Sun-Lim Choi, Tae-Hyung Kim, Jin-A Lee, HyongKyu Kim, Hyoung Kim, Deok-Jin Jang, Jennifer J. Lee, Sunghoon Lee, GwangSik Sin, Chang-Bae Kim, Yutaka Suzuki, Sumio Sugano, Tai Kubo, Leonid L. Moroz, Eric R. Kandel, Jong Bhak, and Bong-KiunKaang. PNAS, 2008, 105(47):18602-18607.

64) The Effect of Histidine Residue Modification on Tyrosinase Activity and Conformation: Inhibition Kinetics and Computational Prediction. Lin Gou, Zhi-Rong Lu, Daeui Park, Sang Ho Oh, Long Shi, Seong Jin Park, Jong Bhak, Yong-Doo Park, Zhen-Long Ren and FeiZou.Journal of Biomolecular Structure & Dynamics, 2008, 26(3):395-401.

63) Structural Bioinformatics Analysis of Disease-related Mutations. Seong-Jin Park, Sangho Oh, Daeui Park and Jong Bhak.Genomics & Informatics, 2008(September), 6(3):142-146.

62) Identification of gene-related Korean patents and construction of a database sever for Korean patent sequences. Byungwook Lee, SeonKyu Kim, Tae Hyung Kim, Sangsoo Kim, Gee Chan Ryu and Jong Bhak.BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, 2008, 13(2):248-251.

61) MassNet: a functional annotation service for protein mass spectrometry data. Daeui Park, Byoung-chul Kim, Seong-Woong Cho, Seong-Jin Park, Jong-Soon Choi, Seung Il Kim, Jong Bhak, and Sunghoon Lee.Nucleic Acids Research, 2008, 1-5.

60) Cyanobacterial hybrid kinase SLL0043 regulates phototaxis by suppressing pilin and twitching motility protein. Bong-Jeong Shin, Jeehyun Oh, Sungsoo Kang, Young-Ho Chung, Young Mok Park, Young Hwan Kim, Seungil Kim, Jong Bhak, and Jong-Soon Choi.JOURNAL OF MICROBIOLOGY, 2008, 46(3):300-308.

59) Automatic synthronization and distribution of biological databases and software over low-bandwidth networks among developing countries. UnitsaSangket, AmornratPhongdara, WilaiwanChotigeat, Darran Nathan, Woo-Yeon Kim, Jong Bhak, ChumpolNgamphiw, SissadesTongsima, Asif M. Khan, Honghuang Lin, and Tin Wee Tan.Bioinformatics, 2008, 24(2):299-301.

58) Pocket extraction on proteins via the Voronoi diagram of spheres. Donguk Kim, Cheol-HyungCho, Youngsong Cho, JoonghyunRyu, JonghwaBhak, and Deok-Soo Kim.Journal of Molecular Graphics &Modelling, 2008, 26(7):1104-1112. (SCI)

57) Predicting the Interactome of Xanthomonasoryzaepathovaroryzae for target selection and DB service. Jeong-Gu Kim, Daeui Park, Byoung-Chul Kim, Seong-Woong Cho, Yeong Tae Kim, Young-Jin Park, Hee Jung Cho, Hyunseok Park, Ki-Bong Kim, Kyong-Oh Yoon, Soo-Jun Park, Byoung-Moo Lee and Jong Bhak.BMC Bioinformatics,2008, 9:41.

56) SNP@Promoter: A database of human SNPs (Single Nucleotide Polymorphisms) within putative promoter region. Byoung-Chul Kim, Woo-Yeon Kim, Daeui Park, Won-Hyong Chung, Kwang-sik Shin and Jong Bhak*. BMC Bioinformatics, 13 Feb. 2008, 9:S1-S2.

55) SynechoNET: integrated protein-protein interaction database of a model cyanobacterium /Synechocystis/ sp. PCC 6803. Woo-Yeon Kim*, Sungsoo Kang*, Byoung-Chul Kim, Jeehyun Oh, Seongwoong Cho, Jong Bhak§ , and Jong-Soon Choi§. BMC Bioinformatics, 13 Feb. 2008, 9:S1-S20.

54) Proteomic approaches to the analysis of atopic dermatitis and new insights from interactomics. Yong-Doo Park, Daeui Park, Jong Bhak and Jun-Mo Yang, PROTEOMICS - CLINICAL APPLICATIONS, 2008, 2(3):290-300(2008 Annual Reviews issue).

53) Multi-resolution protein model. Deok-Soo Kim , Bohyung Lee , Chung-In Won , Donguk Kim, JoonghyunRyu , Youngsong Cho, Chong-Min Kim, Sung-Hoon Lee, and JonghwaBhak. LECTURE NOTES IN COMPUTER SCIENCE, 2007, 4706(2):639-652.

52) GS2PATH: A web-based integrated analysis tool for finding functional relationships using gene ontology and biochemical pathway data. Jin Ok Yang, Charny Park, Byungwook Lee, Sangsoo Kim, Jong Bhak*, and Hyun Goo Woo.Bioinformation, Dec. 30, 2007, 2(5):194-196.

51) Biological Object Downloader (BOD) Service for Easy Download and Management of Biological Databases. Daeui Park, Jungwoo Lee, Giseok Yoon, Sungsam Gong, and Jong Bhak. Genomics & Informatics, Dec. 2007, 5(4):196-199.

50) CONSORF: a consensus prediction system for prokaryotic coding sequences. Sungsoo Kang, Sung-Jin Yang, Sangsoo Kim*, and Jong Bhak*.Bioinformatics, 8 Oct. 2007, 23(22):3088-3090.

49) Genomic Distribution of Simple Sequence Repeats in Brassica rapa. Chang Pyo Hong, Zhong Yun Piao, Tae Wook Kang, Jacqueline Batley, Tae-Jin Yang, Yoon-Kang Hur, Jong Bhak, Beom-Seok Park, David Edwards, and Yong Pyo Lim. Mol. Cells, 6 March 2007, 23(3):349-356.

48) Impact of Transcriptional Properties on Essentiaity and Evolutionary Rate. Jung Kyoon Choi, Sang Cheol Kim, JungminSeo, Sangsoo Kim and Jong Bhak, Genetics, January 2007, 175:199-206.

47) Sequence-level analysis of the diploidization process in the triplicated FLOWERING LOCUS C region of Brassica rapa. Yang TJ, Kim JS, Kwon SJ, Lim KB, Choi BS, Kim JA, Jin M, Park JY, Lim MH, Kim HI, Lim YP, Kang JJ, Hong JH, Kim CB, Bhak J, Bancroft I, Park BS. Plant Cell, 2006, 18(6):1339-1347.

46) Parameter selection of pocket extraction algorithm using interaction interface. Kim Chong-Min, Won Chung-In, RyuJoonghyun, Cho Cheol-Hyung, BhakJonghwa, and Kim Deok-Soo. September 2006, Journal of Zhejiang University - Science A, 7(9):1492-1499.

45) BioCC: An Openfree Hypertext Bio Community Cluster for Biology. Sungsam Gong, TaeHyung Kim, Jungsu Oh, Jekeun Kwon, SuAn Cho, Dan Bolser and Jong Bhak. Genomics & Informatics, September 2006, 4(3):125-128.

44) Localizome: a server for identifying transmembrane topologies and TM helices of eukaryotic proteins utilizing domain information. Sunghoon Lee, Byungwook Lee, Insoo Jang, Sangsoo Kim and Jong Bhak. Nucleic Acids Research, April 19, 2006, 34:W99-W103. (ISSN:0305-1048)

43) Functional Annotation and Analysis of Korean Patented Biological Sequences Using Bioinformatics. ByungWook Lee, Tae Hyung Kim, SeonKyu Kim, Sang Soo Kim, Gee Chan Ryu, and Jong Bhak. Mol. Cells, March 2006, 21(2):269-275.

42) HExDB: Human EXonDataBase for Alternative Splicing Pattern Analysis and predicted human gene number. Junghwan Park, Minho Lee, Tae Hyung Kim, Jong Bhak, Genomics &Informatics, September 2005, 3(3):112-117.

41) A protein domain interaction interface database: InterPare. Sungsam Gong, Changbum Park, Hansol Choi, JunsuKo, Insoo Jang, Jungsul Lee, Dan M. Bolser, Donghoon Oh, Deok-Soo Kim, and Jong Bhak. BMC bioinformatics, 2005, 6:207. (ISSN:1471-2105)

40) Euclidean Voronoi diagrams of 3D sphereds and applications to protein structure analysis. Deok-Soo KIM, Youngsong CHO, Donguk KIM, Sangsoo KIM, Jonghwa BHAK and Sung-Hoon LEE. Japan Journal of Industrial and Applied Mathematics, June 2005, 22(2):251-265. (ISSN:0916-7005)

39) BioCovi: A visualization service for comparative genomics analysis, Jungsul Lee, Daeui Park and Jong Bhak. Genomics & Informatics, 2005, 3(2):52-54.

38) Comparative interactomics analysis of protein family interaction networks using PSIMAP (protein structural interactome map).Daeui Park, Semin Lee, Dan Bolser, Michael Schroeder, Michael Lappe, Donghoon Oh and Jong Bhak. Bioinformatics, May 2005, 21(15):3234-3240. (ISSN:1367-4803)

37) PSIbase: a database of protein structural interactome map (PSIMAP).Sungsam Gong, Giseok Yoon Insoo Jang, Dan Bolser, PanosDafas, Michael Schroeder, Hansol Choi, Yoobok Cho, Kyungsook Han, Sunghoon Lee, Hwanho Choi, Michael Lappe, Liisa Holm, Sangsoo Kim, Donghoon Oh, and JonghwaBhak. Bioinformatics, 2005, 21(10):2541-2543. (ISSN:1367-4803)

36) BioSubroutine: an open web server for bioinformatics algorithms and subroutines. Joowon Lee, Hana Kim, Wonhye Lee, Dongil Chung, and Jong Bhak. Genomics & Informatics, March 2005, 3(1):35-38.

35) Architecture of Basic Building Blocks in Protein and Domain Structural Interaction Networks. Hyun S. Moon, JonghwaBhak, Kwang H. Lee and Doheon Lee, Bioinformatics, 2005, 21(8):1479-1486. (ISSN:1367-4803)

34) The association of Alu repeats with the generation of potential AU-rich elements (ARE) at 3'untranslated regions. Hyeong Jun An, Doheon Lee, KwangHyung Lee and JonghwaBhak. BMC Genomics, 21 Dec. 2004, 5:97 p.1-5. (ISSN : 1471-2164)

33) The Atom of Evolution. JonghwaBhak, Dan Bolser, Daeui Park, Yoobok Cho, Kiesuk Yoon, Semin Lee, SungSam Gong, Insoo Jang, Changbum park, Maryana Huston, and Hwanho Choi. Genomics & Informatics, December 2004, 2(4):167-173.

32) Using convex hulls to extract interaction interfaces from known structures. PanosDafas, Dan Bolser, JacekGomoluch, Jong Park, and Michael Schroeder. Bioinformatics, 2004, 20(10):1486-1490. (ISSN:1367-4803)

31) High correlation between Alu elements and the conversion of 3 UTR of mRNAs processed pseudogenes. Hyeong Jun An, Dokyun Na, Doheon Lee, KwangHyung Lee, and JonghwaBhak. Genomics & Informatics, June 2004 , 2(2):86-91.

30) HPID: The Human Protein Interaction Database. Kyungsook Han, Byungkyu Park, Hyongguen Kim, Jinsun Hong and Jong Park. Bioinformatics, Apr. 29th, 2004, Vol. 20(15):2466-2470. (ISSN:1367-4803)

29) Large scale co-evolution analysis of Protein Structural Interlogues using the global Protein Structural Interactome Map(PSIMAP).Wankyu Kim, Dan M. Bolser, and Jong Park. Bioinformatics, 2004 Feb. 5th, 20(7):1138-1150. (ISSN : 1367-4803, Impact Factor : 5.742)

28) Biological Network Evolution Hypothesis Applied to Protein Structural Interactome. Dan M. Bolser and Jong Park, Genomics & Informatics, September 2003, Vol. 1(1) 7-19.

27) Challenges and New Approaches in Genomics and Bioinformatics. Jong Park and Kyungsook Han. Genomics & Informatics, September 2003, Vol. 1(1) 1-6.

26) Visualisation and Graph-theoretic Analysis of a Large-scale Protein Structural Interactome. Dan M Bolser, PanosDafas, Richard Harrington, Jong Park, and Michael Schroeder. BMC Bioinformatics, 8 October 2003, 4;45 p.1-22. (ISSN:1471-2105)

25) Visualization and Analysis of Protein Interactions. ByonghyonJu, Byungkyu Park, Jong Park, and Kyungsook Han. Bioinformatics, 2003, 19(2):317-318. (ISSN:1367-4803)

24) Predicting Protein Interactions in Human by Homologous Interactions in Yeast. Hyongguen Kim, Jong Park and Kyungsook Han. Lecture Notes in Computer Science, 2003, Vol.2637, 159-165. (ISSN:0302-9743)

23) Large Scale Statistical Prediction of Protein-Protein Interaction by Potentially Interacting Domain (PID) Pair. Wankyu Kim, Jong Park, and JungkeunSuh. Genome Informatics, 2002, 13: 42-50.

22) InterViewer: Dynamic Visualization of Protein-Protein Interactions. Kyungsook Han, ByonghyonJu, and Jong Park. Lecture Notes in Computer Science, 2002, Vol.2528, 364-365. (ISSN:0302-9743)

21) Sequence similarity between stereocilin and otoancorin points to a unified mechanism for mechanotransduction in the mammalian inner ear. Luca Jovine, Jong Park, and Paul M Wassarman. BMC Cell Biology, 2002, 3:28 (ISSN-NO:1471-2121)

20) Protein Interactions in the Whole Human Genome. Kyungsook Han, Byunggyu Park, Hyongguen Kim, Hongjin Kim, and Jong Park. Genome Informatics, 2002, Vol.13, 318-319 (Poster presentation).

19) An Integrated Bioinformatic Search Server: Sequences, Structure, Interaction, and Function of Proteins (SSIF) Server. Jaehyung Lee, InsongKoh, Jong Park. Genome Informatics, 2001, 12: 480-481.

18) Protein Classification Comparison Server. Junhyung Park, SungryongRyu, Cheolmin Kim, InsongKoh, andJong Park. Genome Informatics, 2001, 12: 350-351.

17) Conservation of Protein Interaction Network in Evolution. Jong Park and Dan Bolser. Genome Informatics, 2001, 12:135-140.

16) Generating protein interaction maps from incomplete data: application to fold assignment. Lappe M., Park J., Niggemann O., and Holm L. Bioinformatics, 2001, Vol.17 Suppl.1, S149-S156. (ISMB 2001 paper printed in Bioinformatics) (ISSN:1367-4803)

15) Mapping protein family interactions: intramolecular and intermolecular protein family interaction repertoires in the PDB and yeast. Park J, Lappe M. and Teichmann SA. Journal of Molecular Biology, 2001 Mar, 30;307(3):929-938. (ISSN : 0022-2836, Impact Factor : 5.542)

14) PartsList: a web-based system for dynamically ranking protein folds based on disparate attributes, including whole-genome expression and interaction information. Qian J., Stenger B., Wilson CA., Lin J., Jansen R., Teichmann SA., Park J., Krebs WG., Yu H., Alexandrov V., Echols N., and Gerstein M. Nucleic Acids Res., 2001, 29(8):1750-1764. (ISSN:0305-1048)

13) A fully automatic evolutionary classification of protein folds: Dali domain dictionary version 3.Dietmann S., Park J., Notredame C., Heger A., Lappe M., and Holm L. Nucleic Acids Res., 2001 Jan, 29(1):55-57. (ISSN:0305-1048)

12) Estimating the significance of sequence order in protein secondary structure prediction. Jong Park, Sabine Dietmann, Andreas Heger, and Liisa Holm. Bioinformatics, 2000, 16(11):978-987. (for Issue 9) (ISSN:1307-4803)

11) Fast assignment of protein structures to sequences using the intermediate sequence library PDB-ISL. Sarah A. Teichmann, Cyrus Chothia, George M. Church, and Jong Park, Bioinformatics, 2000, 16(2), 117-124. (ISSN:1367-4803)

10) DaliLite workbench for protein structure comparison. Liisa Holm and Jong Park. Bioinformatics, 2000, Vol 16. Issue 6, p566-567. (ISSN:1367-4803)

9) RSDB: representative sequence databases with high information content. Jong Park, Liisa Holm, Andreas Heger, and Cyrus Chothia. Bioinformatics, 2000 May, Vol 16. Issue No. 5. 458-464. (ISSN:1367-4803)

8) Sequence Search Algorithm Assessment and Testing Toolkit (SAT). Jong Park, Liisa Holm, and Cyrus Chothia. Bioinformatics, 2000, Vol 16. No.2, 104-110. (ISSN:1367-4803)

7) Sequence Comparisons Using Multiple Sequences Detect Three Times as Many Remote Homologues as Pairwise Methods. Park J., Karplus K., Barrett C., Hughey R., Haussler D., Hubbard T. and Chothia C., Journal of Molecular Biology, 11, Dec, 1998, 284(4):1201-1210. (ISSN:0022-2836)

6) Structural assignments to the proteins of Mycoplasma genitalium show that they have been formed by extensive gene duplications and domain rearrangements. Sarah Teichmann, Jong Park, and Cyrus Chothia, PNAS, 8, Dec, 1998, 95(25):14658-14663.

5) DIVCLUS: an automatic method in the GEANFAMMER package that finds homologous domains in single- and multi-domain proteins. Jong Park and Sarah Teichmann.Bioinformatics, 1998, 14(2):144-50. (ISSN:1367-4803)

4) Intermediate sequences find distant sequence homologues. Jong Park, Sarah A. Teichmann, Tim Hubbard and Cyrus Chothia. Journal of Molecular Biology, 17, Oct, 1997, 273(1):349-354. (ISSN:0022-2836)

3) Protein structure prediction: Playing the fold. Hubbard T, Park J., LahmA., Leplae R. and Tramontano A.TRENDS IN BIOCHEMICAL SCIENCES, 1996 Aug, 21(8):279-281. (ISSN:0968-0004)

2) Update on protein structure prediction: results of the IRBM 1995 workshop. Hubbard T., Tramontano A., Barton G., Jones D., Sippl M., Valencia A., Lesk A., Moult J., Rost B., Sander C., Schneider R., Lahm A., Leplae R., Buta C., Eisenstein M., Fjellstr^m O., Floeckner H., Grossman G., Hansen J., HelmerCitterich M., Joergensen F.S., Marchler-Bauer A., Osuna J., Park J., Reinhardt A., Ribas de Pouplana L., Rojo-Dominguez A., Saudek V., Sinclair J., Sturrock S., Venclovas C., Vinals C. 1996, Folding and Design, 1(3), 55-63. (ISSN-NO:1359-0278)

1) Fold recognition and ab initio structure predictions using Hidden Markov Models and beta-strand pair potentials. Tim Hubbard and Jong Park.Proteins, 1995 Nov, 23(3):398-402.

 

 

 

 

 

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